THCV (Tetrahydrocannabivarin)

THCV Tetrahydrocannabivarin Header

THCV (Tetrahydrocannabivarin)

This post is also available in: Français (French)

A non-intoxicating cannabinoid generally found in cannabis in only trace amounts is THCV (Tetrahydrocannabivarin). Not much is known about the effects of this cannabinoid on humans.

THCV Molecule
Tetrahydrocannabivarin (THCV) is a non-intoxicating cannabinoid typically found in cannabis only in trace amounts.

What is THCV?

One of a number of phytocannabinoids, or cannabinoids found in the cannabis plant is THCV (Tetrahydrocannabivarin), which is neither as well researched or as prominent as the major phytocannabinoids CBD (cannabidiol) and THC (tetrahydrocannabinol.

A system of messenger molecules, cannabinoid receptors and enzymes that play an important role in maintaining the body’s homeostasis, or internal regulatory balance, known as the endocannabinoid system (ECS) are how phytocannabinoids interact with the human body. Producing therapeutic and psychoactive effects, phytocannabinoids interact with our body’s cannabinoid receptors and other targets.

THCV has several potential therapeutic benefits that may limit the psychoactivity of THC, though it is less prominent and lesser-known than CBD and THC.


How THCV works

THCV is synthesized in the cannabis trichomes, the glandular hairs found on the surface of the plant, like all other phytocannabinoids. CB1 and CB2 receptors, the most studies cannabinoid receptors in the body, allow THCV to bind to them.

What is THCV
In many ways, THCV lives in the shadows compared to other cannabinoids.

Can THCV get you high?

Compared to other cannabinoids, in many ways, THCV lives in the shadows. The molecule’s effects and potential are just beginning to be examined by research. Largely dependent on dosing, THCV’s psychoactive potential is complex. THCV is not yet available as an isolated concentrate on its own so the question is a bit of a moot point, given its low concentration in cannabis strains. The high is built in since many strains high in THCV are also high in THC.


What are the benefits of THCV?

THCV shows great potential to treat several diseases and improve a number of physical functions. The cannabinoid’s beneficial aspects at low doses while it has the opposite effect at higher levels is one thing that confused researchers however. Several studies, both on animal and human subjects, have identified a variety of potential therapeutic uses for the cannabinoid, though more research is needed to fully understand the scope of THCV’s effects on the human body:

  • Anticonvulsant: THCV may be able to reduce seizure activity in epileptic patients , concluded by a 2015 review published in the Journal of Clinical Pharmacy and Therapeutics.
  • Anti-inflammatory: THCV reduced inflammation and related pain in mice as found by a 2010 study in the British Journal of Pharmacology.
  • Glucose regulator and appetite-suppressant: THCV provides appetite suppression and glycemic control as said by a review of existing studies published in 2020 by the Journal of Cannabis Research. The reviewed studies looked at diabetes and obesity in humans and mice.
  • Bone growth stimulant: According to a study conducted on tissue samples and published in 2007 by Calcified Tissue International, THCV is one of several cannabinoids that may promote bone healing and health .
  • Neuroprotective: THCV has neuroprotective properties that may be useful in treating Parkinson’s disease as concluded by a 2020 study on mice published in the journal Neurobiology of Disease. THCV showed potential in the treatment of neuroinflammation and Huntington’s disease as shown by another 2020 study in the British Journal of Pharmacology.


Where can you buy THCV?

THCV is attracting more and more attention from consumers and cannabis businesses alike, given the potentially powerful and unique effects of the cannabinoid. With the exception of a few strains, mostly African Sativas, however, the biggest challenge with THCV is that it is not naturally produced in high concentrations. It’s difficult to find a pure THCV extract or products like an isolated THCV oil because of this. A more generic full-spectrum cannabis extract or oil that includes THCV in its cannabinoid profile is your best bet.

Marijuana Canadian Money
The biggest challenge with THCV is that it is not naturally produced in high concentrations.

What strains have THCV?

Most strains have THCV show up in relatively low concentrations. There are a handful of easily recognized strains with elevated levels however. These strains include African Sativas such as Durban Poison, Red Congolese, and other landraces most notably.

Other high-THCV strains include:

  • Girl Scout Cookies
  • Pineapple Purps
  • Skunk #1
  • Doug’s Varin
  • Tangie
  • Jack the Ripper
  • Power Plant

This post is also available in: Français (French)

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